|
KMID : 1145520160020020069
|
|
Journal of Radiopharmaceuticals and Molecular Probes
2016 Volume.2 No. 2 p.69 ~ p.72
|
|
|
A pyrazolopyrimidine-based radioligand for imaging of the translocator protein
|
|
Kwon Young-Do
Kim Hee-Kwon
|
|
|
Abstract
|
|
|
|
Since the translocator protein (TSPO) is involved in neurodegeneration diseases, many scientists' interest has been focused on the development of a ligand targeting TSPO. A novel compound based on pyrazolo[1,5 -a] pyrimidine structure, DPA-714, has been studied and considered as a TSPO ligand with high affinity. In this highlight review, several researches for the novel radioligand for the translocator protein are illustrated.
|
|
|
KEYWORD
|
|
|
DPA-714, Translocator protein, Positron emission tomography (PET), Pyrazolo[1, 5 -a]pyrimidine, PET radiotracer
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|